NR 507 Week 4 Collaboration Cafe; Cardiovascular Involvement in SLE Pathophysiology
Course: NR 507 Advanced Pathophysiology Institution: General University Contributor: Josh Hutcherson Format: DOCX/PPTX Pages: 2
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Pathophysiology of Cardiovascular Involvement in SLE The cardiovascular complications in SLE are largely due to systemic inflammation, autoimmunity, and endothelial dysfunction. Studies have shown that inflammation causes the formation of atherosclerotic plaques and promotes cardiovascular events, such as myocardial infarction and stroke (Justiz et al., 2023). The immune complexes in SLE can directly damage blood vessels, leading to vascular complications like vasculitis and endothelial injury, which contribute to the development of cardiovascular disease in SLE patients (Kostopoulou et al., 2
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