NR 546 Week 2 Discussion; Histamine
Course: NR 546 Advanced Pharmacology: Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner Institution: Chamberlain University Students Contributor: Will Smith Format: DOCX/PPTX Pages: 2
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1.Histamine is a water soluble monoamine with the formula C5H9N3 and produced majorly by mast cells from bone marrow. Histamine has four receptors; H1, H2, H3 and H4 which are involved in hypersensitivity reactions, lymphocyte cytokine productions, functions of blood-brain barrier and cytokine generation respectively (kemp, 2020). Histamine plays important role in the pathogenesis and progression or other- wise of allergic diseases including allergic asthma, rhinitis and atopic dermatitis with the differential regulation of T-helper lymphocytes playing a major role in this process (Thangam et
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