NR 567 Week 8 Final Exam Study Guide.

Course: NR 567 Advanced Pharmacology for the Adult-Gerontology Acute Care Nurse Institution: Chamberlain University Students Contributor: James Kent Format: DOCX/PPTX Pages: 4

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NR567 Final Exam Study Guide Therapeutic dosing and monitoring of warfarin (Coumadin) & Types of anticoagulants- mechanisms of action and indications for use Blood coagulation mechanisms: injury exposes subendothelial matrix proteins (i.e. collagen and von Willebrand factor)result in platelet adherence and activation, secretion and synthesis of vasoconstrictors and platelet-recruiting and activating molecules [thromboxane A2 is synthesized from acid within platelets; platelets secrete ADP (a platelet aggregator) and serotonin (stimulates aggregation and vasoconstriction)] = platelet plug C

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