Histamine is a water soluble monoamine with the formula C5H9N3 and produced majorly by mast cells from bone marrow. Histamine has four receptors; H1, H2, H3 and H4 which are involved in hypersensitivity reactions, lymphocyte cytokine productions, functions of blood-brain barrier and cytokine generation respectively (kemp, 2020).
Histamines have been linked to Schizophrenia.
Symptoms of Schizophrenia
Typical antipsychotics are a class of drug used in treating schizophrenia and they include chlorpromazine, haloperidol, olanzapine, clozapine and more. They are basically antagonist as they act by antagonizing dopamine receptors.
